Zode et al., Glia 2009
(Glaucoma) :
Gremlin stimulation of ECM required activation of TGF-beta receptor and R-Smad3 Zhu et al., Nephrol Dial Transplant 2010
(MAP Kinase Signaling System) :
Triptolide inhibits extracellular matrix protein synthesis by suppressing the Smad2 but not the MAPK pathway in TGF-beta1 stimulated NRK-49F cells ... Smad2 inhibition by siRNA significantly reduced ECM synthesis