Schmeck et al., Inflammation 2003
:
Therefore, RhoA/Rac1/Cdc42 contribute to NF-kappaB dependent LPS- and TNFalpha induced expression of PGHS-2 in EC but had no effect on the activity of expressed COX-1 and COX-2
Kamon et al., EMBO J 2006
:
LPS increased the activity of RhoB, but not of RhoA, Cdc42 , or Rac1/2 in a manor dependent on LPS-TRIF- but not LPS-Myd88 signaling
Yao et al., Biochim Biophys Acta 2011
(Lung Injury) :
LPS activated both Rac1 and Rac2, but not CDC42 or RhoA activities in lungs, and specific inhibition of Rac activities by NSC23766 effectively alleviated LPS induced injury