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BLK — PTK2

Pathways - manually collected, often from reviews:

• NCI Pathway Database CXCR4-mediated signaling events: Src Family Kinases-active (FGR/LYN/LCK/YES1/BLK/HCK/SRC/FYN) → FAK (PTK2) (modification, activates) Wang et al., Blood 2000, Zhang et al., Blood 2001, Okabe et al., J Hematother Stem Cell Res 2002, Le et al., J Immunol 2005
  Evidence: mutant phenotype, assay, physical interaction
• WikiPathways Focal Adhesion: BLK/EGFR/ERBB2/FGR/FLT1/HCK/IGF1R/KDR/MET/PDGFRA/PDGFRB/PTK6/SRMS/TXK/TESK2/STYK1/TNK2/TNK1 → PTK2 (activation)