Gene interactions and pathways from curated databases and text-mining

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G6PC — GCG

Text-mined interactions from Literome

Azzout-Marniche et al., Am J Physiol Regul Integr Comp Physiol 2007 : These effects are mainly due to the ability of high physiological concentrations of portal blood amino acids to counteract glucagon induced liver G6PC1 but not PEPCK gene expression
Kodama et al., Biochem J 2007 : We have now demonstrated that PXR also represses glucagon activated transcription of the G6Pase ( glucose-6-phosphatase ) gene by directly binding to CREB [ CRE ( cAMP-response element ) -binding protein ]
Kobayashi et al., Acta Med Okayama 1988 : Glucagon increased the activity of glucose 6-phosphate ( EC 3.1.3.9 ) ( G6Pase ) in the presence or absence of insulin, while insulin had no effects on the levels of G6Pase and fructose 1,6-bisphosphatase ( EC 3.1.3.11 ) in the presence or absence of glucagon
Fleig et al., Arch Biochem Biophys 1984 : Glucose-6-phosphatase activity declining linearly during hormone-free culture was stimulated by glucagon
Bhattacharya et al., Mol Cell Biochem 1993 : Glucagon increased the activities of alanine amino transferase ( AAT ), fructose-1 : 6-bisphosphatase ( fru-P2ase ) and glucose-6-phosphatase (G-6-Pase) in goat brain tissue by about 100 %, 150 % and 50 % respectively