Gene interactions and pathways from curated databases and text-mining

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ASS1 — GCG

Text-mined interactions from Literome

Husson et al., Endocrinology 1982 : Effects of glucocorticosteroids and glucagon on argininosuccinate synthetase , argninosuccinase, and arginase in fetal rat liver ... Results obtained by injected combinations of inducers indicated that a glucocorticosteroid-glucagon interaction might be involved in the regulation of argininosuccinate synthetase and argininosuccinase
Husson et al., Biochem J 1983 : Introduced alone, glucagon induced an increase of ASL activity, but did not affect the ASS activity
Tamura et al., J Gastroenterol 1994 (Amino Acid Metabolism, Inborn Errors) : These results indicate that glucagon significantly increases the urinary excretion of urea in the late onset form of argininosuccinate synthetase deficiency and that it may also decrease plasma NH3 levels in some patients with the deficiency