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IL10 — LANCL1

Text-mined interactions from Literome

Haskó et al., Shock 2000 (Inflammation...) : The down-regulation of IL-12 p40 by spermine was independent of enhancement of IL-10 by this agent, for spermine retained its ability to suppress IL-12 production in peritoneal macrophages obtained from IL-10-deficient mice
Peng et al., J Leukoc Biol 2000 : Morphine enhanced mRNA expression of interleukin (IL)-12 p40 and tumor necrosis factor alpha (TNF-alpha) compared with controls, whereas IL-10 levels were unchanged by drug treatment
Schuetze et al., Int Immunol 2005 : Whereas p19 was induced early and transiently, p40 and p35 were up-regulated later and then continuously, but the secretion of IL-23 and IL-12p70 was significantly reduced by IL-10
Jozefowski et al., Immunology 2005 : Consistent with the effects of leukotriene antagonists, exogenous LTB ( 4 ) enhanced LPS stimulated IL-10 release by approximately 39 % and inhibited IL-12 p40 release by approximately 22 %
Setiawan et al., Infect Immun 2007 (Strongylida Infections) : IL-10 blockade in vitro with anti-IL-10 receptor (IL-10R) monoclonal antibody restored LPMC IFN-gamma and IL-12 p40 secretion
Selvaraj et al., J Clin Immunol 2008 (Genetic Predisposition to Disease...) : The extended genotype bbaaTT ( baT haplotype ) was associated with decreased IL-12p40 and IFN-gamma levels and significantly increased IL-10 levels ( p < 0.05 )
Kramp et al., Clin Exp Immunol 2011 (Tuberculosis) : TNF-a treatment induced a decrease in TNF-a, IL-12p40 and IL-10 mRNA levels in peritoneal cells following PPD stimulation while live M. tuberculosis caused an increase in TNF-a mRNA and a decrease in the IL-10 mRNA expression
Liu et al., Gastroenterology 2011 (Colitis) : Blocking IL-10 receptors increased production of IFN-? and IL-12/23p40 whereas exogenous IL-10 suppressed these cytokines
Elcombe et al., PloS one 2013 : We further show that the reduction in IL-10 production in the MSK1/2 macrophages results in increased secretion of IL-12p40 in response to zymosan relative to wild type controls
Hino et al., Eur J Immunol 1996 : In our experiments, p40 mRNA accumulation was shown to be affected by IL-10 more severely than the accumulation of p35 mRNA, indicating that IL-10 regulates IL-12 production by APC mainly by affecting p40 mRNA accumulation