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C1R — C3

Pathways - manually collected, often from reviews:

• KEGG Phagosome: C3 → C1R (protein-protein, binding/association)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: Complex of 33 proteins (in vivo) Nauta et al., Eur J Immunol 2003*