Gene interactions and pathways from curated databases and text-mining

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IL4 — PTGS1

Text-mined interactions from Literome

Cho et al., Mol Immunol 2011 : Although IL-4 did not affect COX-1 expression, it specifically inhibited LPS induced COX-2 biosynthesis at mRNA and protein levels
Endo et al., J Immunol 1996 : In contrast, cyclooxygenase-1 protein and mRNA were hardly detected in monocytes that were incubated with or without LPS in the presence or absence of IL-4 , IL-10, and IL-13
Longo et al., Mediators Inflamm 1998 : The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation