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CXCL16 — IL4
Text-mined interactions from Literome
Thomas et al., J Immunol 2004
(Bronchial Hyperreactivity) :
In lymphocytes restimulated with CXCL9 and allergen in vitro,
CXCL9 down-regulated
IL-4 expression and up-regulated IFN-gamma expression, suggesting that CXCL9 is able to direct activated lymphocytes toward a Th1-type phenotype
Méndez-Samperio et al., Mediators Inflamm 2006
:
We found that, although M. bovis BCG induced gene expression of CXCL-8 and CXCL-10 in M. bovis BCG infected human epithelial cells,
CXCL-8 mRNA level was significantly
reduced by
IL-4 , whereas no significant effect of IL-4 was observed on CXCL10 mRNA level ... Furthermore, we found a similar
effect of
IL-4 on M. bovis BCG induced
CXCL-8 and CXCL-10 secretion by using other human epithelial A549 cell line
Hosokawa et al., Clin Exp Immunol 2007
(Chronic Disease...) :
On the other hand,
IL-4 and IL-13
inhibited the IL-1beta induced
CXCL16 production by HGFs. Inhibitors of A disintegrin and metalloprotease ( ADAM)10 and ADAM17, a recently identified protease of CXCL16, reduced the amount of CXCL16 released from HGFs
Huang et al., Am J Physiol Lung Cell Mol Physiol 2007
:
IL-4 stimulates the expression of
CXCL-8 , E-selectin, VEGF, and inducible nitric oxide synthase mRNA by equine pulmonary artery endothelial cells