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CYBA — TNF
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Dusi et al., Eur J Immunol 2001
:
Our results indicate that in monocytes the IFN-gamma- and
TNF-alpha induced expression of gp91phox and
p22phox , but not p47phox, requires the binding of PU.1 to gp91phox promoter
Gertzberg et al., Am J Physiol Lung Cell Mol Physiol 2004
:
TNF treatment ( 50 ng/ml for 4.0 h )
induced 1 ) p47phox translocation, 2 ) an increase in
p22phox protein, 3 ) increased localization of p47phox with p22phox, 4 ) O2-* generation, and 5 ) increased permeability to albumin ... p22phox antisense oligonucleotide prevented the
TNF induced effect on
p22phox , p47phox, O2-*, and permeability
Cassatella et al., J Clin Invest 1989
(Granulomatous Disease, Chronic...) :
Tumor necrosis factor and immune interferon synergistically
induce cytochrome b-245 heavy-chain gene expression and nicotinamide-adenine dinucleotide phosphate hydrogenase oxidase in human leukemic myeloid cells