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IFI44 — RELA
Text-mined interactions from Literome
Rodriguez-Kern et al., Neurochem Int 2003
:
The BDNF dependent activation of
NF-kappaB and up-regulation of GLT-1 was critically
dependent on the upstream activation of
p42/p44 MAP kinase signaling, whereas the inhibition of these MAP kinases dramatically increased the Abeta dependent activation of NF-kappaB and production of GLT-1
Li et al., Cancer Res 2006
(Multiple Myeloma) :
The secretion of IL-6 by BMSCs was completely inhibited by 10 ( -9 ) mol/L PACAP, which also attenuated the phosphorylation of both
p42/44 and p38 mitogen activated protein kinases ( MAPK ) as well as
nuclear factor-kappaB (NF-kappaB) activation in response to the adhesion of multiple myeloma cells to BMSCs, whereas the inhibition of p42/44 MAPK signaling attenuated PACAP action
Yamauchi et al., Int Immunol 2007
(Genetic Predisposition to Disease...) :
Thus,
Ifi202 is an important
NF-kappaB activator in DCs and involved in IL-12 production, which may account for a T ( h ) 1-prone phenotype of BWF1 mice
Fang et al., Exp Eye Res 2007
:
Inhibition of
p42/44 activity by PD98059 significantly
reduced LA-induced activation of
NF-kappaB
Yang et al., Molecular vision 2007
(Radiation Injuries) :
These results also suggest that p38,
p44/42 , and JNK may regulate glial induced photoreceptor death and that p38, JNK, and
NF-kappaB may
regulate photoreceptor induced microglial activation