◀ Back to IL6
AGTR1 — IL6
Text-mined interactions from Literome
Street et al., J Endocrinol 2003
:
Both IGFBP-2 and IGFBP-4 were
reduced by IL-1beta and
IL-6 in combination
at 1 and 10 ng/ml ( P < 0.05 )
Schieffer et al., J Am Coll Cardiol 2004
(Coronary Artery Disease...) :
Angiotensin converting enzyme (ACE) inhibition and
angiotensin II type 1 receptor (AT1) blockade reduced serum MMP-9 protein/activity to a similar extent, and only AT1 blockade
reduced hsCRP,
IL-6 , and platelet aggregation in patients with CAD
Kandalam et al., Regul Pept 2010
:
Our study showed for the first time that Ang II
induced JAK2/STAT3 phosphorylation and
IL-6 secretion through activation of the Ang II
AT(1) receptor in brainstem astrocytes
Nakamura et al., Eur J Oral Sci 2011
(Gingivitis) :
Therefore, in the present study the expression of the angiotensin II type 1 receptor (AT1R) was investigated in inflamed human gingival tissue, and the possible
involvement of the
AT1R in interleukin-1ß (IL-1ß) induced
interleukin-6 (IL-6) production by cultured human gingival fibroblasts ( HGFs ) was also studied ... The data suggest that the
AT1R may be
involved in the regulation of gingival inflammation by modulating IL-1ß induced
IL-6 production in HGFs
Franchimont et al., Endocrinology 1997
:
IL-6 did not modify IGF-I messenger RNA ( mRNA ) levels, but when tested in the presence of IL-6sR, IL-6
at 1 to 100 ng/ml
increased IGF-I transcripts by up to 3.2-fold after 24 h.
IL-6sR caused a small increase in IGF-I mRNA levels when tested alone