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ANG — BCL2
Text-mined interactions from Literome
Paudel et al., J Virol 2012
:
Silencing
ANG or inhibiting its nuclear translocation
resulted in decreased nuclear LANA-1 and ANG levels, decreased interactions between ANG-LANA-1, ANG-p53, and LANA-1-p53, the induction of p53, p21, and Bax proteins, the increased cytoplasmic localization of p53, the downregulation of
Bcl-2 , the increased cleavage of caspase-3, and the apoptosis of cells
Yang et al., Clin Exp Pharmacol Physiol 2012
:
In addition,
Ang- ( 1-7 ) inhibited AngII induced accumulation of cleaved caspase 3 and
enhanced the expression of the anti-apoptotic factor
Bcl-2 at both the mRNA and protein levels