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CDH5 — TNF

Text-mined interactions from Literome

Hofmann et al., Eur J Med Res 2002 : We investigated whether TNF-alpha regulates the synthesis of VE-cadherin on the transcriptional level ... Our results indicate that TNF-alpha affects VE-cadherin gene expression on the transcriptional level, inducing a downregulation of the VE-cadherin expression
Nwariaku et al., Shock 2002 : The purpose of our study was to determine the effect of TNFalpha on VE-cadherin cell-surface expression and to identify the signaling pathways involved in TNF induced changes in cadherin expression ... The purpose of our study was to determine the effect of TNFalpha on VE-cadherin cell-surface expression and to identify the signaling pathways involved in TNF induced changes in cadherin expression ... Inhibition of p38 but not ERK MAPK significantly reduced the effect of TNFalpha on endothelial permeability and cell-surface VE cadherin expression
Ferrero et al., FASEB J 2004 (Capillary Leak Syndrome...) : Studies of the mechanism of action showed that CgA inhibits TNF induced VE-cadherin down-regulation and barrier alteration of cultured endothelial cells, in an indirect manner
Nwariaku et al., Blood 2004 : We found that tumor necrosis factor (TNF) caused tyrosine phosphorylation of VE-cadherin , separation of lateral cell-cell junctions, and intercellular gap formation in human umbilical vein endothelial cell ( HUVEC ) monolayers ... Finally, adenoviral delivery of the kinase dead PAK1 ( K298A ) decreased TNF induced JNK activation, VE-cadherin phosphorylation, and lateral junctional separation, consistent with the proposed involvement of PAK1 upstream of the NADPH oxidase
Ding et al., Int Immunopharmacol 2005 : Furthermore, it was found that ESM attenuated the disorganization of vascular endothelial (VE)-cadherin induced by TNF-alpha
Angelini et al., Am J Physiol Lung Cell Mol Physiol 2006 : TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia ... PP2 also blocked TNF-alpha induced tyrosine phosphorylation of VE-cadherin , gamma-catenin, and p120(ctn)
Böckeler et al., J Infect Dis 2007 (Marburg Virus Disease) : We showed that mediators released from MARV infected monocytes/macrophages, as well as recombinant tumor necrosis factor (TNF)- alpha /H2O2 and interferon (IFN)- gamma, caused tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 ( PECAM-1 ) but not of the vascular endothelial (VE) cadherin/catenin complex proteins
Vandooren et al., Arthritis Rheum 2008 (Rheumatic Diseases) : In vitro, cadherin 11 expression by FLS was consistently up-regulated by tumor necrosis factor alpha (TNFalpha) at the protein, but not the messenger RNA, level
Cain et al., J Cell Biol 2010 : We find that depletion of p110alpha but not other p110 isoforms decreases TNF induced endothelial permeability, Tyr phosphorylation of the adherens junction protein vascular endothelial cadherin ( VE-cadherin ), and leukocyte TEM
Parfiniewicz et al., Acta Pol Pharm 2012 : However, TNF-alpha did not cause such a significant increase in sE-cadherin level