Gene interactions and pathways from curated databases and text-mining

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ASIP — JUN

Text-mined interactions from Literome

Harada et al., Jpn J Pharmacol 1999 : Z-Asp-CH2-DCB , a caspase inhibitor with anti-apoptotic activity, did not inhibit the induction and phosphorylation of c-Jun
Camandola et al., J Neurochem 2000 : The broad-spectrum caspase inhibitor N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl ketone and the caspase-3 inhibitor N-acetyl-Asp-Glu-Val-Asp-aldehyde blocked HNE induced increases in AP-1 DNA binding activity, demonstrating a requirement for caspase activation in the activation of AP-1
Peng et al., Blood 2004 : AP1 binding absolutely required Arg218, Asp222 , and Glu225