Heller et al., J Biol Chem 2012
:
Chimeric receptor chains of the ?C tail fused to the IL-13Ra1 extracellular and transmembrane domain did not elicit robust IRS-2 phosphorylation in response to IL-13 suggesting that the extracellular/transmembrane domains of the IL-4/IL-13 receptor, not the cytoplasmic domains, control signaling efficiency
Sozzani et al., Biochem Biophys Res Commun 1998
:
We demonstrate for the first time that IL-13 induces the association of IRS-2 with PLC-gamma 1