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CD36 — IL13

Text-mined interactions from Literome

Berry et al., Eur J Immunol 2007 : IL-13 induces expression of CD36 in human monocytes through PPARgamma activation ... We also show that CD36 induction by IL-13 via PPARgamma is dependent on phospholipase A2 activation and that IL-13 induces the production of endogenous 15-deoxy-Delta12,14-prostaglandin J2, an endogenous PPARgamma ligand, and its nuclear localization in human monocytes
Yakubenko et al., Circ Res 2011 : IL-13 treatment upregulates 15-LO dependent CD36 expression on human monocytes ; our studies showed that ß ( 2 ) integrin activation and a ( M ) integrin clustering significantly inhibited IL-13 dependent CD36 mRNA and protein expression, as well as CD36 related foam cell formation
Yakubenko et al., J Biol Chem 2013 (Atherosclerosis) : Moreover, inhibition of Jak2, Tyk2, or their downstream target 15-LO with antisense oligonucleotides profoundly inhibits IL-13 induced CD36 expression and CD36 dependent foam cell formation, whereas13 ( S ) Hydroperoxyoctadecadienoic acid ( HPODE ), a 15-LO product and peroxisome proliferator activated receptor-? ligand, completely restores CD36 expression in monocytes treated with 15-LO antisense