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IFNG — KRT17
Text-mined interactions from Literome
Wei et al., J Pathol 1999
(Psoriasis) :
The
IFN-gamma induced epidermal expression of
keratin 17 and TGk could be completely blocked by culturing the biopsies in the presence of IL-1ra or anti-IL-1 antibodies, while the induction of HLA-DR and ICAM-1 was not inhibited
Bonnekoh et al., Skin Pharmacol Appl Skin Physiol 2001
(Psoriasis) :
Dithranol and dimethylfumarate suppress the
interferon-gamma induced up-regulation of
cytokeratin 17 as a putative psoriasis autoantigen in vitro ... Preincubation with a subcytotoxic and antiproliferative dithranol concentration as low as 0.3 microM for 2 h prior to the IFN-gamma exposure resulted in a K17 expression that was significantly lower than the
IFN-gamma induced
K17 expression reference level ... The
IFN-gamma induced
K17 expression was also significantly lowered by coincubation with a subcytotoxic and nonantiproliferative concentration of 3 microM dimethylfumarate
Flohr et al., Eur J Immunol 1992
:
Interferon-gamma regulates expression of a novel
keratin class I gene
Bockelmann et al., Skin Pharmacol Physiol 2005
(Psoriasis) :
Acitretin as an established antipsoriatic drug and the tyrosine kinase inhibitor imatinib decreased, whereas hydrocortisone as well as dexamethasone increased the
IFN-gamma induced
K17 overexpression
Chang et al., Proc Soc Exp Biol Med 1987
(Carcinoma, Squamous Cell) :
Immunohistochemical staining of these `` tumoroids '' with a differentiation specific, anti-keratin antibody indicated that
IFN-gamma enhanced expression of this
keratin
Bonnekoh et al., J Invest Dermatol 1995
(Psoriasis) :
Up-regulation of
keratin 17 expression in human HaCaT keratinocytes by
interferon-gamma ... The immortalized human keratinocyte cell line HaCaT was used to assess the
effect of
interferon-gamma (IFN-gamma) on expression of keratin
K17 ... These data suggest that aberrant
K17 expression observed in psoriatic lesions may be a
consequence of
IFN-gamma overexpression, and that the HaCaT cell line may be a useful in vitro model system to elucidate the underlying mechanisms
Vogel et al., Eur J Biochem 1995
(Psoriasis) :
Transcriptional
activation of psoriasis associated cytokeratin
K17 by
interferon-gamma ... The acid cytokeratin
K17 is
inducible by
interferon-gamma (IFN-gamma) , a characteristic unique for cytokeratins analysed so far