Gene interactions and pathways from curated databases and text-mining

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IFNG — KRT17

Text-mined interactions from Literome

Wei et al., J Pathol 1999 (Psoriasis) : The IFN-gamma induced epidermal expression of keratin 17 and TGk could be completely blocked by culturing the biopsies in the presence of IL-1ra or anti-IL-1 antibodies, while the induction of HLA-DR and ICAM-1 was not inhibited
Bonnekoh et al., Skin Pharmacol Appl Skin Physiol 2001 (Psoriasis) : Dithranol and dimethylfumarate suppress the interferon-gamma induced up-regulation of cytokeratin 17 as a putative psoriasis autoantigen in vitro ... Preincubation with a subcytotoxic and antiproliferative dithranol concentration as low as 0.3 microM for 2 h prior to the IFN-gamma exposure resulted in a K17 expression that was significantly lower than the IFN-gamma induced K17 expression reference level ... The IFN-gamma induced K17 expression was also significantly lowered by coincubation with a subcytotoxic and nonantiproliferative concentration of 3 microM dimethylfumarate
Flohr et al., Eur J Immunol 1992 : Interferon-gamma regulates expression of a novel keratin class I gene
Bockelmann et al., Skin Pharmacol Physiol 2005 (Psoriasis) : Acitretin as an established antipsoriatic drug and the tyrosine kinase inhibitor imatinib decreased, whereas hydrocortisone as well as dexamethasone increased the IFN-gamma induced K17 overexpression
Chang et al., Proc Soc Exp Biol Med 1987 (Carcinoma, Squamous Cell) : Immunohistochemical staining of these `` tumoroids '' with a differentiation specific, anti-keratin antibody indicated that IFN-gamma enhanced expression of this keratin
Bonnekoh et al., J Invest Dermatol 1995 (Psoriasis) : Up-regulation of keratin 17 expression in human HaCaT keratinocytes by interferon-gamma ... The immortalized human keratinocyte cell line HaCaT was used to assess the effect of interferon-gamma (IFN-gamma) on expression of keratin K17 ... These data suggest that aberrant K17 expression observed in psoriatic lesions may be a consequence of IFN-gamma overexpression, and that the HaCaT cell line may be a useful in vitro model system to elucidate the underlying mechanisms
Vogel et al., Eur J Biochem 1995 (Psoriasis) : Transcriptional activation of psoriasis associated cytokeratin K17 by interferon-gamma ... The acid cytokeratin K17 is inducible by interferon-gamma (IFN-gamma) , a characteristic unique for cytokeratins analysed so far