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ATF4 — SOD1

Text-mined interactions from Literome

Oh et al., J Neurochem 2008 (Amyotrophic Lateral Sclerosis) : Expression of the mutant SOD1 caused signs of both early and late ER stress responses, namely, RNA dependent protein kinase-like ER kinase and eukaryotic initiation factor alpha phosphorylation, Jun amino-terminal kinase activation, activating transcription factor 6-translocation, X-box binding protein 1 mRNA splicing, and caspase 12 activation
Matus et al., PloS one 2013 : Our results support a functional role of ATF4 in ALS , offering a novel target for disease intervention