Gene interactions and pathways from curated databases and text-mining

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CDKN1A — SIL1

Text-mined interactions from Literome

Drukteinis et al., Placenta 2005 (Choriocarcinoma...) : Immunocytochemistry and Western blot analysis showed that BaP induced expression of nuclear p21CIP1 protein, the major inhibitor of cyclin dependent kinases
Sadikovic et al., Toxicol Appl Pharmacol 2006 (Breast Neoplasms) : Furthermore, BaP increased p53 levels in both p53 positive cell lines, as well as p21 levels in MCF-7 cells, an effect that was prevented by the p53-specific inhibitor pifithrin-alpha