Wang et al., J Biol Chem 1999
:
The present work supports a regulatory role of Ca2+/calmodulin for the activation of Ral-A and suggests a possible direct link between signal transduction pathways of Ca2+/calmodulin and Ral-A proteins
Park et al., Exp Mol Med 2001
:
Ca2+/calmodulin stimulated the GTPase activity of RalA Clough et al., J Biol Chem 2002
:
It was examined whether RalA can bind calmodulin in vivo, whether RalB can bind calmodulin , and whether calmodulin is functionally involved in Ral activation ... We propose that differential binding of calmodulin by RalA and RalB underlies possible functional differences between the two proteins and that calmodulin is involved in the regulation of the activation of Ral-GTPases