Gene interactions and pathways from curated databases and text-mining

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EPHB2 — LGI1

Text-mined interactions from Literome

Kunapuli et al., J Biol Chem 2004 (Glioma...) : LGI1 expression also results in the inhibition of ERK1/2 phosphorylation but not p38 phosphorylation
Kunapuli et al., Genomics 2010 (Brain Neoplasms...) : LGI1 is a secreted protein, and when the culture supernatant from cells expressing FLAG- and GFP tagged proteins were applied to parental T98G cells, ERK/MAPK1 phosphorylation and cell mobility was suppressed , demonstrating that the LGI1 protein acts as a suppressive agent for cell movement in this assay