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EGF — NCK1
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
NCK1
→
EGF
(increases)
Olsen et al., Cell 2006*
Evidence: We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database
Text-mined interactions from Literome
Li et al., Mol Cell Biol 1992
(Cell Transformation, Neoplastic) :
Here we show that
epidermal growth factor or platelet derived growth factor stimulation of intact human or murine cells
leads to phosphorylation of
Nck protein on tyrosine, serine, and threonine residues
Tang et al., Oncogene 1997
:
This study suggests that the GAP associated p62 acts as an SH2 domain docking protein and mediates the interaction between
Nck and EGF receptor in
response to
EGF stimulation