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BMP2 — SLC22A3

Text-mined interactions from Literome

Okagawa et al., Dev Biol 2007 : These results provide evidence that BMP signaling through the AV endocardium is required for the EMT and the activation of the BMP receptor in the endocardium can promote AV EMT in the chick
Ohta et al., Development 2007 : These indicate that the inhibition of Bmp signaling by temporal and/or spatial Nog expression suppresses EMT and leads to the cessation of the ingressive cell movement from the VER at the end of gastrulation
Yan et al., Am J Pathol 2010 (Cicatrix...) : Moreover, TNF-alpha induced EMT was impaired by antagonists against bone morphogen proteins (BMP) 2/4, suggesting that BMP mediates the TNF-alpha induced EMT in human skin
Chen et al., Pathol Oncol Res 2011 (Neoplasm Invasiveness...) : Then pretreatment of Panc-1 cells with LY294002, an inhibitor of the PI3K/AKT pathway, significantly inhibited BMP-2 induced EMT and invasiveness
Townsend et al., Cells Tissues Organs 2011 : Consistent with the activation of the Par6/Smurf1 pathway downstream of TGFßR3, targeting ALK5, Par6, or Smurf1 significantly inhibited EMT in response to either TGFß2 or BMP-2
Townsend et al., Cell Signal 2012 : The Type III TGFß receptor ( TGFßR3 ) is required for TGFß2- or BMP-2 stimulated EMT in atrioventricular endocardial cushion ( AVC ) explants in vitro but the mediators downstream of TGFßR3 are not well described
Bai et al., Development 2013 (Truncus Arteriosus, Persistent...) : To directly address the function of Vegfa repression in Bmp mediated EMT , we performed ex vivo explant cultures from Bmp4/7 and miR-17-92 mutant hearts