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GRAP2 — IL11

Text-mined interactions from Literome

Ling et al., Crit Care Med 2002 : In contrast to its effects on the janus kinase/STAT pathways, interleukin-6 activation of MAP kinases ( extracellular signal regulated kinase-1, extracellular signal regulated kinase-2, and p38 ) was unaffected by endotoxin
Yan et al., J Biol Chem 2002 : This model probiotic also inhibits activation of the pro-apoptotic p38/mitogen activated protein kinase by tumor necrosis factor, interleukin-1alpha , or gamma-interferon
Scicchitano et al., Blood Cells Mol Dis 2008 (MAP Kinase Signaling System) : In addition, these results suggest that IL-6, IL-11 , GM-CSF, G-CSF and Activin A are similarly regulated by p38 and NF-kappaB and that the MEK1, JNK and PKC pathways appear to play a more limited role in modulating cytokine expression in HBMSC
Rasheed et al., Arthritis Res Ther 2010 (Osteoarthritis) : Pomegranate extract inhibits the interleukin-1ß induced activation of MKK-3, p38a-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes
Shin et al., Carcinogenesis 2012 (Neoplasm Invasiveness) : These results suggest that both the PI3K and Raf pathways are necessary for the expression of IL-11 in oncogenic Ras mutated cells, and that JNK, p38 and Stat3 also contribute to oncogenic Ras induced IL-11 expression