Gene interactions and pathways from curated databases and text-mining

◀ Back to EPHB2

EPHB2 — PAPSS1

Text-mined interactions from Literome

El-Shewy et al., Mol Endocrinol 2012 (Diabetic Nephropathies...) : Pretreating cells with SK inhibitor, dimethylsphinogsine or down-regulation of SK1 and SK2 revealed that LDL dependent activation of ERK1/2 and JNK is mediated by SK1
Gault et al., J Biol Chem 2012 (Cell Transformation, Neoplastic) : Because SK1 activity and subcellular localization have been shown to be regulated by ERK , we wished to investigate the effect of oncogenic Ras, a potent activator of the Raf/MEK/ERK pathway, on the activity of SK1 and sphingolipid metabolism