◀ Back to EPHB2
EPHB2 — PAPSS1
Text-mined interactions from Literome
El-Shewy et al., Mol Endocrinol 2012
(Diabetic Nephropathies...) :
Pretreating cells with SK inhibitor, dimethylsphinogsine or down-regulation of SK1 and SK2 revealed that LDL dependent activation of
ERK1/2 and JNK is
mediated by
SK1
Gault et al., J Biol Chem 2012
(Cell Transformation, Neoplastic) :
Because
SK1 activity and subcellular localization have been shown to be
regulated by
ERK , we wished to investigate the effect of oncogenic Ras, a potent activator of the Raf/MEK/ERK pathway, on the activity of SK1 and sphingolipid metabolism