Gene interactions and pathways from curated databases and text-mining

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EPHB2 — HTR2C

Text-mined interactions from Literome

Werry et al., Biochem Pharmacol 2008 (MAP Kinase Signaling System) : In conclusion, we provide evidence for remarkable flexibility in 5HT(2C)R mediated ERK1/2 signaling that can be pharmacologically and mechanistically distinct depending on the agonist or edited isoform involved and on the duration of receptor activation
Li et al., Neurochem Int 2010 : ERK ( 1/2 ) phosphorylation induced by stimulation of either 5-HT(2B) or 5-HT(2C) receptors was mediated by epidermal growth factor (EGF) receptor transactivation ( Peng et al., this issue ), shown by the inhibitory effect of AG1478, an inhibitor of the EGF receptor tyrosine kinase, and GM6001, an inhibitor of Zn-dependent metalloproteinases, and thus of 5-HT(2B) receptor mediated EGF receptor agonist release