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HDAC3 — IL8
Text-mined interactions from Literome
Gilmour et al., Am J Physiol Lung Cell Mol Physiol 2003
:
PM ( 10 ) and H ( 2 ) O ( 2 ) increased
IL-8 protein release from A549 cells after 24-h treatment, and this was
enhanced by
histone deacetylase inhibition by trichostatin A ( cotreatment )
Chavey et al., Mol Pharmacol 2008
(Breast Neoplasms) :
In addition, blocking NF-kappaB pathway by adenoviral delivery of a dominant negative IkappaBorIkappaB kinase complex 2 (IKK2) mutant abolished
IL-8 gene
induction by
histone deacetylase inhibitors
Rehni et al., Naunyn Schmiedebergs Arch Pharmacol 2012
(Opioid-Related Disorders...) :
The present study has been designed to investigate the effect of selective inhibitors of
histone deacetylase and/or N-acetyl-Asp-Glu-Val-Asp-al ( Ac-DEVD-CHO ), a selective
interleukin-1ß converting enzyme
inhibitor , on the development of naloxone induced opioid withdrawal syndrome both in vitro and in vivo and the effect of histone deacetylase inhibition on histone H3 acetylation in brain
Winkler et al., Pulm Pharmacol Ther 2012
(Inflammation...) :
Interestingly, siRNA mediated reduction of
HDAC3 resulted in increased production of
IL8 and IL1ß in response to LPS stimulation, while HDAC2 knockdown had no effect on either cytokine
Venza et al., Pigment Cell Melanoma Res 2013
(Melanoma...) :
Here, we explored the
effects of the novel class II-specific
histone deacetylase inhibitors ( HDACis ) MC1568 and MC1575 on
interleukin-8 (IL-8) expression and cell proliferation in cutaneous melanoma cell line GR-M and uveal melanoma cell line OCM-3 upon stimulation with phorbol 12-myristate 13-acetate ( PMA )