Gene interactions and pathways from curated databases and text-mining

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EPHB2 — LRP6

Text-mined interactions from Literome

Webb et al., J Cell Sci 2000 (Fibrosarcoma...) : By regulating the uPA/uPAR system, LRP may also regulate ERK activation, cellular migration, and invasion
Ma et al., J Cell Biol 2002 : In addition to Rac1, LRP-1 suppressed activation of extracellular signal regulated kinase ( ERK ) in MEFs ; however, it was Rac1 ( and not ERK ) that was responsible for the effects of LRP-1 on MEF migration ... Thus, LRP-1 regulates two signaling proteins in the same cell ( Rac1 and ERK ), both of which may impact on cell migration