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GP5 — INS

Text-mined interactions from Literome

Maddux et al., Diabetes 2000 (Insulin Resistance) : Plasma cell membrane glycoprotein-1 ( PC-1 ) inhibits insulin receptor (IR) tyrosine kinase activity and subsequent cellular signaling
Komori et al., Endocrinology 1992 : Insulin dependent tyrosine phosphorylation of a monomeric 195K glycoprotein ( pp195 ) was observed in wheatgerm agglutinin ( WGA ) -Sepharose purified insulin receptor preparations from rat liver and muscle
Grarup et al., Diabetologia 2006 (Diabetes Mellitus, Type 2...) : Plasma cell membrane glycoprotein 1 ( PC-1 ) inhibits insulin signalling by direct interaction with the insulin receptor alpha subunit
Schiess et al., Mol Cell Proteomics 2009 : The data revealed insulin dependent cell surface glycoprotein dynamics, including insulin receptor internalization, and linked these changes to intracellular signaling networks
Liu et al., Eur J Pharmacol 2009 : Insulin regulates P-glycoprotein in rat brain microvessel endothelial cells via an insulin receptor mediated PKC/NF-kappaB pathway but not a PI3K/Akt pathway ... Our previous study showed that insulin restored impaired function and expression of P-glycoprotein in diabetic blood-brain barrier, and further study showed that insulin up-regulated P-glycoprotein expression and function in normal blood-brain barrier, so insulin might be one of the factors that regulated the function and expression of P-glycoprotein in blood-brain barrier of diabetes ... In this study, the intracellular pathways that insulin regulated the P-glycoprotein were investigated using primarily cultured rat brain microvessel endothelial cells model
Zhou et al., Eur J Pharmacol 2009 : Plasma cell membrane glycoprotein-1 , or ectonucleotide pyrophosphatase/phosphodieterase ( PC-1/ENPP1 ) has been shown to inhibit insulin signaling in cultured cells in vitro and in transgenic mice in vivo when overexpressed
Tang et al., Chin Med J (Engl) 2009 : P-glycoprotein regulating biphasic insulin secretion in rat pancreatic beta cells
Margolis et al., Biol Neonate 1990 : In contrast, insulin stimulated phosphorylation of a Mr 120 kd glycoprotein derived from rat liver membranes, known as pp120/HA4 and more recently identified as ecto-ATPase, was not observed in fetal liver until day 17 of gestation
Yu et al., J Biol Chem 1987 : Insulin stimulates the tyrosine phosphorylation of a Mr = 160,000 glycoprotein in rat adipocyte plasma membranes
Sharma et al., Inflammation 1985 (Diabetes Mellitus, Experimental...) : Extracellular glycoproteins play an important role in wound healing ; yet little is known about glycoprotein biosynthesis and its regulation by insulin in inflammation
Kandror et al., Proc Natl Acad Sci U S A 1994 : We have isolated and partially sequenced a M ( r ) 160,000 glycoprotein whose rate of cycling to and from the adipocyte cell surface is enhanced by insulin in a manner apparently identical to the effect of insulin on GLUT4 cycling
Barraud et al., Inflammation 1996 : Effects of insulin , dexamethasone and cytokines on alpha 1-acid glycoprotein gene expression in primary cultures of normal rat hepatocytes ... While the effects of insulin , dexamethasone and cytokines on alpha 1-acid glycoprotein gene expression have been investigated in various hepatoma cell lines, the individual and combined effects of these components on the expression of this gene have been rarely studied in cultured normal rat hepatocytes