Gene interactions and pathways from curated databases and text-mining

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AQP7 — INS

Text-mined interactions from Literome

Kishida et al., J Biol Chem 2000 : Insulin dose-dependently suppressed AQPap mRNA expression in 3T3-L1 cells ... Accordingly, negative regulation of AQPap expression by insulin was impaired in the insulin-resistant state
Rodríguez et al., J Clin Endocrinol Metab 2011 (Obesity...) : The translocation of AQP in response to insulin and isoproterenol was analyzed by immunocytochemistry ... Insulin up-regulated all AQP , whereas leptin up-regulated AQP3 and down-regulated AQP7 and AQP9 in adipocytes and hepatocytes ... Our findings show, for the first time, that insulin and leptin regulate the AQP through the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway in human visceral adipocytes and hepatocytes
Louchami et al., Cell Physiol Biochem 2012 : A new role for aquaporin 7 in insulin secretion