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CD40LG — CXCL12
Text-mined interactions from Literome
Yu et al., J Bone Miner Res 2003
(Bone Resorption) :
Conversely, RANKL, but not
SDF-1 ,
promoted RAW-OC development,
TRAP activity, cathepsin K expression, and bone pit resorption, and SDF-1 did not modify these RANKL responses
Kim et al., Arthritis Rheum 2007
(Arthritis, Rheumatoid) :
This study was undertaken to investigate the
effect of interleukin-17 (IL-17) and
CD40-CD40L interaction on
SDF-1 production in RA fibroblast-like synoviocytes ( FLS )
D'Aversa et al., J Neurosci Res 2008
(AIDS Dementia Complex...) :
CD40-CD40 ligand interactions in human microglia
induce CXCL8 ( interleukin-8 ) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator protein-1 (AP-1)
Borge et al., Cancer Immunol Immunother 2013
(Leukemia, Lymphocytic, Chronic, B-Cell) :
CXCL12 increases the proliferation and the expression of CD25, CD69,
CD154 , and IFN? on CD3 stimulated CD4 ( + ) T cells from CLL patients, similarly in T cells from ZAP-70 ( + ) to ZAP-70 ( - ) patients