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FOS — SFTPC

Text-mined interactions from Literome

Berger et al., Proc Natl Acad Sci U S A 1995 (Niemann-Pick Diseases) : Here we show that SPC increased specific DNA binding activity of transcription activator AP-1 in electrophoretic mobility-shift assays ... Since the increase in AP-1 binding activity preceded the increase in c-fos mRNA, posttranslational modifications may be important in mediating the early SPC induced increases in AP-1 DNA binding activity ... Since the expression of many proteins with diverse functions is known to be regulated by AP-1, SPC induced activation of AP-1 may contribute to the pathophysiology of Niemann-Pick disease
Berger et al., Biochim Biophys Acta 1998 : We previously demonstrated that the sphingolipid, sphingosylphosphocholine (SPC) increased DNA binding activity of AP-1 proteins accompanying cellular proliferation