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NFKB1 — RET

Text-mined interactions from Literome

Ludwig et al., Cancer Res 2001 (Carcinoma, Medullary...) : RET induced NF-kappaB and IKKbeta activity requires Ras function but does neither involve the classical mitogen activated protein kinase kinase/extracellular signal regulated kinase nor the phosphoinositide 3-kinase/Akt pathways ... In contrast, RET induced NF-kappaB activity is dependent on Raf and MEKK1
Ludwig et al., Oncogene 2003 : Overexpression of Grap-2 inhibits RET induced NF-kappaB activation , and cotransfection of Grap-2 significantly reduces focus formation induced by oncogenic RET in NIH 3T3 cells
Gallel et al., Hum Pathol 2008 (Carcinoma, Medullary...) : The results also support the hypothesis that RET activation by somatic or germ line mutations may be responsible for NF-kappaB activation in MTCs