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NFKB1 — PRL
Text-mined interactions from Literome
Telleria et al., J Mol Endocrinol 2004
:
Furthermore,
NFkappaB DNA binding activity was
enhanced by
prolactin in luteinized granulosa cells
Lee et al., Cancer Res 2005
(MAP Kinase Signaling System) :
Our studies showed that 16-kDa
PRL specifically
blocked IRF-1 but not
NF-kappaB signaling to the iNOS promoter
Um et al., J Biol Chem 2006
(Neuroblastoma) :
In these cells
Prl treatment strongly activates the STAT5, AKT, and MAPK signaling pathways and
induces weak activation of the p65
NF-kappaB factor
Boutet et al., J Dairy Sci 2007
(Mastitis, Bovine) :
Prolactin activated
NF-kappaB ; maximal NF-kappaB activation was weaker with PRL than with TNF-alpha at 30 or 180 min poststimulation
Sodhi et al., Cytokine 2008
:
It is further shown that p38 MAP kinase, STAT3 and
NF-kappaB could
play a differential regulatory role in
PRL or GH induced production of cytokines by macrophages