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CD44 — NFKB1

Text-mined interactions from Literome

Gruber et al., Mol Immunol 2005 : Consistently, after CD3/CD28 engagement, deficiency of PKCepsilon did not impair NF-kappaB transactivation as well as CD25, CD44 and CD69 induction
Gore et al., J Biol Chem 2008 : We show that in B lymphocytes, MIF initiates a signaling cascade that involves Syk and Akt, leading to NF-kappaB activation, proliferation, and survival in a CD74- and CD44 dependent manner
Bourguignon et al., J Biol Chem 2009 (Breast Neoplasms) : Further analyses indicate that activation of SIRT1 ( deacetylase ) by resveratrol ( a natural antioxidant ) induces SIRT1-p300 association and acetyltransferase inactivation, leading to deacetylation of HA/CD44 induced beta-catenin and NFkappaB-p65 , inhibition of beta-catenin-T-cell factor/lymphocyte enhancer factor and NFkappaB-specific transcriptional activation, and the impairment of MDR1 and Bcl-x ( L ) gene expression
Campo et al., Biochim Biophys Acta 2009 : HA treatment produced different effects : low MW HA up-regulated CD44 expression, increased PKCdelta and PKCepsilon levels, and enhanced inflammation in untreated chondrocytes ; while in PMA treated cells it increased CD44, PKCdelta, PKCepsilon, NF-kB , TNF-alpha, IL-1beta, MMP-13, and iNOS expression and enhanced the effects of PMA ; medium MW HA did not exert action ; high MW HA had no effect on untreated chondrocytes ; however, it reduced PKCdelta, PKCepsilon, NF-kB activation and inflammation in PMA stimulated cells
Damm et al., J Invest Dermatol 2010 (Lymphatic Metastasis...) : HGF dependent CD44v6 regulation in melanocytes is NF-kappaB dependent because BAY 11-7082, an inhibitor of NF-kappaB activation, but not interference with the mitogen activated protein kinase or phosphatidylinositol 3-kinase cascade, antagonized HGF induced CD44v6 expression ... NF-kappaB mediated transcriptional regulation of CD44v6 involves the transcription factors Egr-1 and CCAAT enhancer binding protein-beta ( C/EBP-beta )