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HSPB1 — IL1A

Text-mined interactions from Literome

Saklatvala et al., Biochem J 1991 : IL1 had the same effect on hsp 27 in pig articular chondrocytes, endothelial cells from human umbilical vein and an epidermoid carcinoma cell line ( KB ) ... When cells had been depleted of protein kinase C ( PKC ) by prolonged treatment with PMA, stimulation by IL1 , TNF or bradykinin still increased hsp 27 phosphorylation ... IL1 , TNF and bradykinin each caused hsp 27 phosphorylation by a pathway independent of PKC
Wu et al., Cell Signal 2009 : On the other hand, IL-1beta stimulation reduces endogenous HSP27/TRAF6 association, but inhibiting HSP27 phosphorylation by using SB202190, an inhibitor of p38, and MAPKAPK2 RNAi increases HSP27/TRAF6 association and thereby enhances TRAF6 ubiquitination, IKK phosphorylation as well as NF-small ka, CyrillicB activation