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FCGR3A — IL2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
O'Shea et al., J Immunol 1992
:
Fc gamma RIIIA induced
IL-2R alpha-chain expression was also extremely sensitive to herbimycin A as was antibody dependent cellular cytotoxicity, in fact more so than receptor mediated phosphorylation and calcium mobilization
Behar et al., Protein Eng Des Sel 2008
:
Importantly, the engagement by both molecules of
FcgammaRIIIA expressed by transfected Jurkat T cells or by NK cells derived from peripheral blood
induced a strong
IL-2 and IFN-gamma production, respectively