Ponnappan et al., Exp Gerontol 2004
:
Lowered tyrosine phosphorylation of IkappaBalpha may be due to a decrease in activity of p56 ( lck ) and ZAP-70, since treatment with piceatannol, an inhibitor of syk and src family kinases, mimics age associated decline in tyrosine phosphorylation of IkappaBalpha in T cells from young donors
Imbert et al., Cell 1996
:
Pervanadate induced I kappa B-alpha phosphorylation and NF-kappa B activation required expression of the T cell tyrosine kinase p56ick