◀ Back to IL2

GNRH1 — IL2

Text-mined interactions from Literome

Dixit et al., Biol Reprod 2003 : We did not observe any significant difference in IL-2 and IL-10 production in response to GnRH-Ag
Tanriverdi et al., Clin Exp Immunol 2005 : Finally, we analysed the role of GnRH-I and GnRH-II in IL-2R gamma-chain expression ... Non-radioactive cell proliferation assay was used for proliferation studies and we used quantitative real-time RT-PCR to examine the role of GnRH-I and GnRH-II on IL-2R gamma-chain expression in PMBCs. Treatment of PMBCs with GnRH-I ( 10 ( -9 ) M and 10 ( -5 ) M ) and with interleukin-2 (IL-2) ( 50 U/ml ) resulted in a significant increase in cell proliferation compared with the untreated control ... All these findings strongly suggest that regulation of IL-2R expression may therefore be an important target for GnRH-I and GnRH-II in PMBCs in males ... In summary, present study clearly demonstrates the differential effects of GnRH-I and GnRH-II on PMBC proliferation, IL-2 proliferative response, and IL-2Rgamma expression in PMBCs in males
Batticane et al., Endocrinology 1991 : The specificity of such effect was demonstrated by 1 ) the failure of LHRH fragments [LHRH- ( 1-6 ) ] to mimick the LHRH stimulatory effect ; and 2 ) the complete reversal produced by simultaneous addition of a potent LHRH-ANTA on IL-2 receptor expression induced by LHRH
Karanth et al., Neuroendocrinology 1993 : Consequently, we studied the possible effect of IL-2 on the release of somatostatin and GRH from the mediobasal hypothalamus ( MBH ) in vitro