Gene interactions and pathways from curated databases and text-mining

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FOXO1 — IFI27

Text-mined interactions from Literome

Charvet et al., J Immunol 2006 : Consistent with the important role of FOXO1 in p27 kip1 transcription, stimulated Vav1 ( -/- ) T cells failed to down-regulate the expression of p27 kip1, explaining their G0-G1 arrest
Adachi et al., Gastroenterology 2007 (Liver Cirrhosis, Experimental...) : FoxO1 directly induces the expression of p27 ( kip1 ) and manganese superoxide dismutase ( MnSOD )
Lees et al., Am J Physiol Cell Physiol 2008 : Deletion of a 253-bp portion of the 5'-untranslated region ( UTR ) resulted in a significant decrease in FOXO induced p27 ( Kip1 ) promoter expression ... Site-specific mutation of a daf-16 family protein binding element ( DBE ) within this 253-bp portion of the 5'-UTR also demonstrated a decrease in FOXO induced p27 ( Kip1 ) promoter expression
Jablonska et al., J Neurosci 2012 (Hypoxia, Brain) : Cdk2 activation was essential for the regenerative OPC response after hypoxia and was accompanied by reduced FoxO1 dependent p27 ( Kip1 ) expression