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HMGA2 — MYLIP

Text-mined interactions from Literome

Hebert et al., Molecular cancer 2007 (Carcinoma, Squamous Cell...) : Here we report that HMGA2 expression in head and neck squamous cell carcinoma ( HNSCC ) cells is regulated in part by miRNA-98 (miR-98)
Lee et al., Cell Mol Life Sci 2011 (MAP Kinase Signaling System) : We confirmed that miR-23a , miR-26a and miR-30a inhibit HMGA2 to accelerate the progress of senescence
Zhu et al., Circ Res 2013 (Disease Models, Animal...) : Overexpression of miR-10A* and miR-21 in young EPCs suppressed Hmga2 expression, caused EPC senescence, as evidenced by senescence associated ß-galactosidase upregulation, decreased self-renewal potential, increased p16(Ink4a)/p19(Arf) expression, and resulted in impaired EPC angiogenesis in vitro and in vivo, resembling EPCs derived from aged mice ... In contrast, suppression of miR-10A* and miR-21 in aged EPCs increased Hmga2 expression, rejuvenated EPCs, resulting in decreased senescence associated ß-galactosidase expression, increased self-renewal potential, decreased p16(Ink4a)/p19(Arf) expression, and improved EPC angiogenesis in vitro and in vivo
Rice et al., J Biol Chem 2013 (Lung Neoplasms...) : We showed that the first two highly conserved sites are conducive to HMGA2 repression by miR-33a , establishing HMGA2 as a genuine target of miR-33a
Xiang et al., Pharmazie 2013 : We found that elevated expression of miR-98 led to a higher sensitivity of A549/DDP cells to cisplatin, and the protein level of HMGA2 , was clearly up-regulated in both A549/DDP and A549 cells by miR-98