◀ Back to IFI27
FLI1 — IFI27
Text-mined interactions from Literome
Matsunobu et al., Clin Cancer Res 2004
(Recurrence...) :
Finally, we examined the process of
EWS-Fli1 mediated reduction of
p27 expression ... These data strongly suggest
EWS-Fli1 might
attenuate p27 protein level via activation of the proteasome mediated degradation pathway
Hu et al., J Orthop Res 2008
(Cell Transformation, Neoplastic...) :
In this report, we show that depletion of
EWS/FLI1 in Ewing 's cell lines
results in a senescence phenotype, a marked increase in expression of the G1/S regulatory proteins
p27 ( kip1 ) and p57(kip2), and a significant decrease in cyclin D1 and CDK2