Gene interactions and pathways from curated databases and text-mining

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FLI1 — IFI27

Text-mined interactions from Literome

Matsunobu et al., Clin Cancer Res 2004 (Recurrence...) : Finally, we examined the process of EWS-Fli1 mediated reduction of p27 expression ... These data strongly suggest EWS-Fli1 might attenuate p27 protein level via activation of the proteasome mediated degradation pathway
Hu et al., J Orthop Res 2008 (Cell Transformation, Neoplastic...) : In this report, we show that depletion of EWS/FLI1 in Ewing 's cell lines results in a senescence phenotype, a marked increase in expression of the G1/S regulatory proteins p27 ( kip1 ) and p57(kip2), and a significant decrease in cyclin D1 and CDK2