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IFNG — ITGB1
Text-mined interactions from Literome
Freysdottir et al., Clin Exp Immunol 1999
(Behcet Syndrome...) :
Furthermore, in BD a significantly increased proportion of the gammadelta T cell population expressed CD69 and high levels of
CD29 and were
induced to produce
IFN-gamma and TNF-alpha compared with healthy controls
Wang et al., J Interferon Cytokine Res 2007
(Toxoplasmosis) :
These results indicate that
IFN-gamma induced expression of endothelial VCAM-1 and its binding to
alpha4beta1 integrin on CD8 ( + ) T cells is important for recruitment of the T cells into the brain during the chronic stage of T. gondii infection, although LFA-1/ICAM-1 interaction may also be involved in this process
Boisvert et al., Mol Immunol 2007
:
Alpha2 beta1 integrin signaling
augments T cell receptor dependent production of
interferon-gamma in human T cells ... We demonstrated that ligation of
alpha2 beta1 integrin with Collagen type I ( Coll I ) but not alpha1 beta1 integrin with Collagen IV ( Coll IV ) significantly
augmented T cell receptor ( TCR ) -dependent expression and production of
IFN-gamma by effector T cells ... Inhibition studies indicated that activation of ERK and JNK MAPKs and PI3K/AKT are necessary for both TCR- and
TCR+alpha2 beta1 integrin dependent
IFN-gamma production and that Coll I increases TCR dependent activation of ERK and JNK MAPKs, and AKT
Sasaki et al., Eur J Immunol 2008
(Melanoma, Experimental) :
Notably, the inhibitory effects of IL-4 on Tc1 expression of
VLA-4 could be
blocked by the presence of IL-12, but not
IFN-gamma
Rutenfranz et al., Scand J Immunol 1991
:
In further studies, depletion of T-cell subsets showed that CD3+, CD4+, CD8+,
CD29+ and CD45RA+ cells were
involved in
IFN-gamma production after mitogenic stimulation
Rubio et al., Eur J Immunol 1995
:
We have analyzed the changes in the pattern of beta 1 integrin expression that take place during monocyte activation and demonstrated that lipopolysaccharide (LPS) and
interferon (IFN)-gamma specifically
induce the expression of the
alpha 1/beta 1 integrin , which was detectable on the monocyte membrane as early as 12 h after monocyte activation
Soilu-Hänninen et al., J Neuroimmunol 1995
:
We show that IFN-beta downregulates both basal and
IFN-gamma induced expression of
VLA-4 ( very late activation antigen-4 ) antigen on monocytes, but has no effect on the expression of CD11a, CD11b, CD11c, L-selectin, CD18, ICAM-1, beta 1-integrin or CD44 on monocytes or ICAM-1 on EAhy 926 cells