Gene interactions and pathways from curated databases and text-mining

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IFNG — ITGB1

Text-mined interactions from Literome

Freysdottir et al., Clin Exp Immunol 1999 (Behcet Syndrome...) : Furthermore, in BD a significantly increased proportion of the gammadelta T cell population expressed CD69 and high levels of CD29 and were induced to produce IFN-gamma and TNF-alpha compared with healthy controls
Wang et al., J Interferon Cytokine Res 2007 (Toxoplasmosis) : These results indicate that IFN-gamma induced expression of endothelial VCAM-1 and its binding to alpha4beta1 integrin on CD8 ( + ) T cells is important for recruitment of the T cells into the brain during the chronic stage of T. gondii infection, although LFA-1/ICAM-1 interaction may also be involved in this process
Boisvert et al., Mol Immunol 2007 : Alpha2 beta1 integrin signaling augments T cell receptor dependent production of interferon-gamma in human T cells ... We demonstrated that ligation of alpha2 beta1 integrin with Collagen type I ( Coll I ) but not alpha1 beta1 integrin with Collagen IV ( Coll IV ) significantly augmented T cell receptor ( TCR ) -dependent expression and production of IFN-gamma by effector T cells ... Inhibition studies indicated that activation of ERK and JNK MAPKs and PI3K/AKT are necessary for both TCR- and TCR+alpha2 beta1 integrin dependent IFN-gamma production and that Coll I increases TCR dependent activation of ERK and JNK MAPKs, and AKT
Sasaki et al., Eur J Immunol 2008 (Melanoma, Experimental) : Notably, the inhibitory effects of IL-4 on Tc1 expression of VLA-4 could be blocked by the presence of IL-12, but not IFN-gamma
Rutenfranz et al., Scand J Immunol 1991 : In further studies, depletion of T-cell subsets showed that CD3+, CD4+, CD8+, CD29+ and CD45RA+ cells were involved in IFN-gamma production after mitogenic stimulation
Rubio et al., Eur J Immunol 1995 : We have analyzed the changes in the pattern of beta 1 integrin expression that take place during monocyte activation and demonstrated that lipopolysaccharide (LPS) and interferon (IFN)-gamma specifically induce the expression of the alpha 1/beta 1 integrin , which was detectable on the monocyte membrane as early as 12 h after monocyte activation
Soilu-Hänninen et al., J Neuroimmunol 1995 : We show that IFN-beta downregulates both basal and IFN-gamma induced expression of VLA-4 ( very late activation antigen-4 ) antigen on monocytes, but has no effect on the expression of CD11a, CD11b, CD11c, L-selectin, CD18, ICAM-1, beta 1-integrin or CD44 on monocytes or ICAM-1 on EAhy 926 cells