Gene interactions and pathways from curated databases and text-mining

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IRF6 — SMAD7

Text-mined interactions from Literome

Burke et al., Br J Surg 2010 (Colonic Neoplasms) : LPS reduced whereas TGF-beta1 increased smad-7 expression
Namachivayam et al., Am J Physiol Gastrointest Liver Physiol 2013 (Disease Models, Animal...) : LPS increased Smad7 binding to the TGF-ß ( 2 ) promoter and was associated with dimethylation of the lysine H3K9, a marker of transcriptional silencing, on the nucleosome of TGF-ß ( 2 )