Chiang et al., Nature 2001
:
Insulin stimulated GLUT4 translocation requires the CAP dependent activation of TC10
Rosenblatt-Velin et al., FASEB J 2004
(Insulin Resistance) :
On the other hand, total and phosphorylated Cbl was reduced during insulin resistance, suggesting that activation of Cbl/CAP is essential for insulin mediated GLUT4 translocation, in addition to activation of PI3K