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CA2 — PIK3CA

Text-mined interactions from Literome

Le Blanc et al., Circ Res 2004 (Ion Channel Gating) : Mutants of PI3K transfected into vascular myocytes also revealed the essential role of the lipid-kinase activity of PI3K in Ang II-induced Ca2+ responses
Wang et al., Biochem J 2006 : Moreover, KCl and noradrenaline induced stimulation of PI3K-C2alpha in a Ca2+ dependent manner, but not of p110alpha or p110beta
Wang et al., Biochem J 2007 : We have shown previously that PAR-2 simultaneously promotes Galphaq/Ca2+ dependent activation and beta-arrestin-1 dependent inhibition of class IA PI3K ( phosphoinositide 3-kinase ), and we sought to characterize further the role of beta-arrestins in the regulation of PI3K activity
Misra et al., J Biol Chem 1998 : We conclude that PI3K is involved in alpha2M* induced mitogenesis in macrophages and intracellular Ca2+ plays a role in PI3K activation