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CRK — MAP2K3
Text-mined interactions from Literome
Yasunami et al., Drug Metab Dispos 2004
:
Curcumin, a c-Jun N-terminal kinase (JNK) pathway inhibitor, and anthra [ 1,9-cd ] pyrazole-6 ( 2H ) -one ( SP600125 ), a JNK inhibitor, suppressed the induction of CYP3A4 mRNA by 1,25 ( OH ) ( 2 ) D ( 3 ), but not 2'-amino-3'-methoxyflavone ( PD098059 ), a
mitogen activated protein kinase kinase-extracellular signal regulated kinase ( ERK ) pathway inhibitor, or 4- ( 4-fluorophenyl ) -2- ( 4-methylsulfinylphenyl ) -5- ( 4-pyridyl ) 1H-imidazole ( SB203580 ), a
p38 inhibitor
Wu et al., Cell Microbiol 2006
(MAP Kinase Signaling System) :
Phosphorylation of
MEK3/6 , p38 kinase and ATF-2 was also observed and this pathway was
inhibited by
p38 kinase inhibitors SB203850 and SB202190