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CDKN1A — MIR34A

Text-mined interactions from Literome

Nalls et al., PloS one 2011 (Neoplasm Invasiveness...) : MiR-34a upregulation by these agents also induced acetylated p53, p21 ( WAF1 ), p27 ( KIP1 ) and PUMA in pancreatic CSCs. Inhibition of miR-34a by antagomiR abrogates the effects of 5-Aza-dC and SAHA, suggesting that 5-Aza-dC and SAHA regulate stem cell characteristics through miR-34a
Choi et al., Nat Cell Biol 2011 (Teratoma) : Mir34a deficiency in mice significantly increased reprogramming efficiency and kinetics, with miR-34a and p21 cooperatively regulating somatic reprogramming downstream of p53