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CDKN1A — IGFBP3

Text-mined interactions from Literome

Boyle et al., J Urol 2001 (Prostatic Neoplasms) : In addition, induction of the cyclin dependent kinase inhibitory protein p21/WAF/CIP1 by 1,25- ( OH ) ( 2 ) D ( 3 ) is mediated by IGFBP-3
O'Rear et al., J Mol Endocrinol 2005 : IGFBP-3 increased the cyclin dependent kinase inhibitor p21 expression and this effect was abolished by TGF-beta
Dar et al., J Invest Dermatol 2010 (Melanoma...) : Overexpression of IGFBP3 in melanoma cells in vitro suppressed tumor cell survival, induced apoptosis, reduced colony formation and invasion, and induced expression of the proapoptotic genes p21 , PUMA, and BAX
Lin et al., J Biol Chem 2011 (Carcinoma, Hepatocellular...) : Induction of the cyclin dependent kinase inhibitor p21 by MS-275 was attenuated by IGFBP-3 down-regulation, providing an explanation for IGFBP-3 dependent effects of MS-275 on cell cycle activity